A qualitative and histophotometric investigation
نویسنده
چکیده
Histochemical investigations have been carried out on epithelial mucins in the digestive tract of experimental animals (Martin, 1961; Gerard, 1964) and human subjects (Hoskins and Zamcheck, 1963; Schrager, 1964; Lev and Spicer, 1965; Lev, 1965), and different histochemical properties of these mucins have been observed in different parts of the gastrointestinal tract. Preliminary observations in the large bowel have shown the presence of two types of epithelial acid mucins: sialomucins and sulphated mucopolysaccharides (Lev and Spicer, 1965). The other investigations were mostly confined to the gastric mucosa. It was therefore decided to study the goblet cells of the large bowel both in normal subjects and in patients with ulcerative colitis to see if any histochemical differences could be found. Colon
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